• Jue Zhang, Liejun Mei, Fubing Wang, and Yan Li.
• Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, PR. China.
• Medicine (Baltimore). 2020 Dec 4; 99 (49): e23404.

RationaleOne of the most distinctive features of epithelial ovarian cancer is tendency to disseminate into peritoneal cavity to form peritoneal carcinomatosis, indicating advanced disease with poor prognosis.Patient ConcernsA fifty-year-old patient had a chief complaint of an abdominal distension lasting 1 month.DiagnosesThe patient was diagnosed with advanced epithelial ovarian cancer with peritoneal carcinomatosis by computed tomography scan, tumor markers, endoscopy examination, and pathology.InterventionsThe patient was treated with cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy followed by 8 cycles of systemic chemotherapy.OutcomesTill March 9, 2020, the patient has disease-free survival over 10 years.LessonsThe application of cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy combined with systematic chemotherapy may improve survival dramatically for the patients with epithelial ovarian cancer and peritoneal carcinomatosis and should be considered as an option of a relatively new regime.

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