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- Hui-Lin Guan, Yu Wang, Yi-Fang Gui, and Chun-Lei Zhang.
- Department of Scientific Research, Mudanjiang Medical University.
- Medicine (Baltimore). 2020 Dec 4; 99 (49): e23463.
BackgroundData supporting the use of Chinese herbal medicine compound (CHMC) on breast hyperplasia (BH) based on the data from previous studies. However, the results are still contradictory. Thus, this study aims to compare the results obtained for effect on case-controlled study (CCS) of CHMC on BH.MethodsThis study will include CCS assessing the effect of CHMC on BH. A literature search will be carried out in Cochrane Library, MEDLINE, EMBASE, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from inception to the present. We will not apply language limitation to any electronic database. Study quality will be evaluated using Newcastle-Ottawa Scale, and statistical analysis will be performed using RevMan 5.3 software.ResultsThis study will summarize the up-to-date evidence to assess the effect of CHMC on BH.ConclusionThe results of this study may exert helpful evidence to determine whether CHMC is effective on BH. OSF REGISTRATION NUMBER:: osf.io/3k8ch.
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