• Min Liu, Meinian Liu, Wenlong Yang, Ou Mei, Hanting Xia, Hong Tu, Li Wang, Xuyong Deng, and Fengyun Yang.
• The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
• Medicine (Baltimore). 2020 Dec 4; 99 (49): e23483.

BackgroundDe Quervain disease (DQD) is a common clinical disease. As a strainingdisease, DQD is more common in women who frequently engage in manual operations. The main clinical symptoms are local pain and dysfunction. Many clinical studies have reported that moxibustion has a good effect on the treatment of DQD, but there is no relevant systematic review. So the purpose of this study is to evaluate the effectiveness and safety of moxibustion in treating DQD.MethodsThe following 8 electronic databases will be searched, including PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Web of Science, Chinese Scientific Journal Database (VIP), Wanfang Database, and Chinese Biomedical Literatures Database (CBM) from their inception to 1 October 2020 without any restrictions. Researchers retrieve the literature and extracted the data, evaluation of research methods, quality of literature. The outcomes will include a visual analogue scale, Finkelsteins, resisted thumb extension, total effective rate, incidence of any adverse events. We use the Cochrane Risk of a bias assessment tool to evaluate methodological qualities. Data synthesis will be completed by RevMan 5.3.0.ResultsWe will show the results of this study in a peer-reviewed journal.ConclusionsThis meta-analysis will provide reliable evidence for moxibustion treatment of DQD.Inplasy Registration NumberINPLASY2020100111.

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