• Alexander X Tai, Aneil Srivastava, Aalap Herur-Raman, Peter Jih Cheng Wong, and Walter C Jean.
• Department of Neurosurgery, MedStar Georgetown University Hospital, Washington, DC, USA. Electronic address: axt2@georgetown.edu.
• World Neurosurg. 2021 Feb 1; 146: e1335-e1344.

BackgroundVarious minimally invasive approaches, such as supraorbital (SO), minipterional (MPT), and translateral orbital (TLO), can access the paraclinoid region. Studies have described these approaches individually but have not directly compared all of them in the same anatomic specimen.MethodsUsing virtual reality models generated from computed tomography studies of living subjects, we simulated TLO, MPT, and variations of SO approaches, without and with removal of the orbital rim and sphenoid wing. We measured the area of freedom (AOF), distance, and angle of attack to 4 paraclinoid targets: anterior clinoid process, optic foramen, lateral superior orbital fissure, and maxillary strut.ResultsFor superiorly positioned targets, such as anterior clinoid process and optic foramen, MPT provided a larger AOF compared with the supraorbital approach. However, with progressive drilling of the orbital roof and lesser wing of the sphenoid, the SO corridor AOF was equivalent to MPT at the anterior clinoid process and larger at the optic foramen (P = 0.003). To the lateral superior orbital fissure, TLO had the most limited AOF, and MPT had the greatest (P < 0.01 for all comparisons). For the maxillary strut, MPT, TLO, and SO with orbitotomy and sphenoidectomy all provided a similar AOF.ConclusionsFor surgical targets in the paraclinoid region, MPT provided a greater AOF and shorter distance compared with TLO and limited SO approaches. With progressive enlargement of the SO corridor, SO with orbitotomy and sphenoidectomy matched and occasionally superseded the AOF of MPT. However, the AOF to inferomedial targets such as the maxillary strut was similar among all approaches.Copyright © 2020 Elsevier Inc. All rights reserved.

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