• Dtsch. Med. Wochenschr. · Jun 2019

    Review

    [Clostridium Difficile: Monoclonal Antibody Therapy and Vaccines].

    • Emil Christian Reisinger, Meinolf Ebbers, and Micha Löbermann.
    • Dtsch. Med. Wochenschr. 2019 Jun 1; 144 (12): 842-849.

    AbstractHospital-acquired Clostridium difficile infections have become much more frequent in recent years. Besides treatment with antibiotics and fecal microbiota transplant, new preventive strategies are available now. Bezlotoxumab is an antibody against toxin B and may reduce the risk of relapse by roughly 10 %. Several vaccine candidates against toxins A and B and surface-associated antigens were immunogenic and are tested in clinical trials to investigate the efficacy and safety.© Georg Thieme Verlag KG Stuttgart · New York.

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