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Journal of neurosurgery · Feb 2016
Case ReportsAnaplastic meningioma: octreotide therapy for a case of recurrent and progressive intracranial disease.
- Richard Rammo, Adam Rock, Andrea Transou, Aditya Raghunathan, and Jack Rock.
- Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Hospital, Detroit, Michigan;
- J. Neurosurg. 2016 Feb 1; 124 (2): 496-500.
AbstractMeningiomas are common intracranial tumors categorized as Grades I-III per the current WHO guidelines. A small percentage of meningiomas are Grades II and III, which are likely to recur after initial treatment. Grade III meningiomas are considered to be malignant and warrant aggressive management. If surgery and radiation fail to produce lasting remission, effective treatment options for patients with progressive anaplastic meningiomas are elusive. The authors present the case of a patient with a meningioma that gradually progressed from Grade I to Grade III over 12 years despite repeated surgery and radiation therapy. The patient has been in remission for over 3 years following octreotide therapy.
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