• N Cailleux, H Lévesque, D Bastit, A Cuvelier, J F Muir, and H Courtois.
• Département de médecine interne, Hôpital de Boisguillaume, CHU, Rouen, France.
• Rev Med Interne. 1998 Jun 1; 19 (6): 434-7.

IntroductionTransfusion-related acute lung injury (TRALI) is an infrequent but life-threatening complication of hemotherapy, usually secondary to passive transfer of antibody from the donor's plasma to the recipient. TRALI is a diagnosis of exclusion often masked by underlying factors.ExegesisWe report a new case of TRALI in a patient with severe multinevritis associated with Sjögren's syndrome and cryoglobulinemia, who had received intravenous immunoglobulins.ConclusionThis case report underlines the difficulty to establish a diagnosis in both acute respiratory failure and intra-alveolar hemorrhage in patients with auto-immune disorders. This case report also emphasizes the necessity of taking precautions in these immunocompromised patients in whom hemoglobin transfusion is required.

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