• Marisa Hernandez-Morgan, Jacques Neelankavil, Tristan Grogan, Bryant Hong, Theodora Wingert, and Emily Methangkool.
• Department of Anesthesiology and Perioperative Medicine, Division of Cardiac Anesthesia, University of California, Los Angeles, CA. Electronic address: marisahernandezmorgan@mednet.ucla.edu.
• J. Cardiothorac. Vasc. Anesth. 2021 Aug 1; 35 (8): 2311-2318.

ObjectivesThe aim of this study was to evaluate the effect of preoperative anemia on early postoperative outcomes in a population of patients undergoing lung transplantation.DesignSingle-center retrospective study of lung transplantation recipients between April 2013 and June 2018. The primary outcome was hospital length of stay.SettingRonald Reagan UCLA Medical Center, Los Angeles, CA, a tertiary academic medical center.ParticipantsPatients presenting from home for lung transplantation.InterventionsNone.Measurements And Main ResultsA total of 435 patients underwent lung transplantation during the study period. After exclusion, 342 were included in the analysis. The prevalence of preoperative anemia was 54% (n = 183); however, only 11% of anemic patients received treatment for anemia before transplantation. Multivariate regression analysis indicated that lower hemoglobin levels were associated with longer hospital lengths of stay (p = 0.049). Preoperative anemia also was independently associated with an increased risk for redo surgery for bleeding (odds ratio 4.89; p = 0.007). No association between preoperative anemia and any of the other postoperative outcomes examined was found.ConclusionsPreoperative anemia in patients undergoing lung transplantation is undertreated and independently associated with an increased risk for redo surgery for bleeding. Additional studies regarding reasons for this association and effect of treatment are necessary to improve outcomes.Copyright © 2020 Elsevier Inc. All rights reserved.

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