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- E Andrews, H Fernández, H Folch, G Eller, and M Pollette.
- Departamento de Microbiología, Universidad de Concepción, Valdivia, Chile.
- Medicina (B Aires). 1996 Jan 1; 56 (5 Pt 1): 487-92.
AbstractUsing a flagellated (052) and an aflagellated (T-1) strains we studied the participation of flagellar epitopes of C. jejuni in the adhesion to HEp-2 cells in vitro. Strain 052 was significantly more adherent than strain T-1. When adhesion assays were carried out with antiflagella monoclonal antibodies, strain 052 showed inhibition of their adhesive capacity that varied between 64.3 and 92.9%. With an ELISA test it was demonstrated that those monoclonal antibodies were specific and directed exclusively against flagellar epitopes of strain 052 being unreactive with strain T-1. Our results show that flagellar epitopes could participate in the adhesion process suggesting that flagella could be involved in the installation of the infectious process.
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