• Rev Assoc Med Bras (1992) · Nov 2020

    Correlation between hepatopulmonary syndrome and oxygen saturation pulse oximetry in cirrhotic patients.

    • Sara Cardoso Paes Rose, Débora Vilela Cunha, Sandra de Barros Cobra Medeiros, José Eduardo Trevizoli, Marcos de Vasconcelos Carneiro, Wladimir Magalhães de Freitas, and Liliana Sampaio Costa Mendes.
    • Serviço de Gastroenterologia do Instituto Hospital de Base, Faculdade de Medicina, Universidade Católica de Brasília, Brasília, DF, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Nov 1; 66 (11): 1577-1582.

    ObjectiveHepatopulmonary Syndrome (HPS) is a complication of cirrhosis that worsens the disease's prognosis, pre and post liver transplant. The objective of this study is to analyze the prevalence of HPS in cirrhotic patients at our service and to correlate it with oxygen saturation (SatO2) using a pulse oximeter to evaluate if this is useful as a screening test for HPS. A prospective study was conducted in patients with hepatic cirrhosis conventionally selected from 2014 to 2016. All the patients underwent an echocardiogram with microbubbles and oxygen saturation measurement by pulse oximetry. Those with intrapulmonary shunt were submitted to arterial blood gas analysis. The relationship between oxygen saturation and HPS was assessed by the multivariate model of binary logistic regression. We analyzed 77 patients, and 23.3% (18 patients) had all criteria for HPS. The relationship between HPS and SatO2 did not show statistical significance, even after the variables were adjusted for sex, age, and smoking. Oxygen saturation alone was not able to detect HPS in the sample of cirrhotic patients. More accurate methods for screening and diagnosis of the syndrome should be used.

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