• Der Internist · Apr 2021

    Case Reports

    [A 3-week history of intestinal symptoms in a 67-year-old male patient with chronic arthralgia].

    • V J Keim, G Zachmann, G Faller, and T Zöpf.
    • Medizinische Klinik 1, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, Deutschland. victor.keim@klinikum-karlsruhe.de.
    • Internist (Berl). 2021 Apr 1; 62 (4): 433-440.

    AbstractWhipple disease is an infection caused by the bacterium Tropheryma whipplei. Due to its unspecific clinical symptoms, it is difficult to diagnose and often remains undetected for a long time. The case of a patient who presented with acute intestinal symptoms to the authors' department is reported. The diagnosis of classic Whipple disease was established. The symptoms subsided under antibiotic therapy. Complications in the form of immune reconstitution inflammatory syndrome (IRIS) occurred, requiring immunosuppressive treatment.

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