• Burns · Aug 2021

    Determining clinically meaningful thresholds for innovative burn care products to reduce autograft: A US burn surgeon Delphi panel.

    • Angela L F Gibson, Janice Smiell, Tzy-Chyi Yu, Elaine A Böing, Erika Brockfeld McClure, Elizabeth Merikle, and James H Holmes.
    • Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
    • Burns. 2021 Aug 1; 47 (5): 1066-1073.

    AbstractReducing the amount of donor skin needed for definitive wound closure can improve outcomes in patients with severe burns. This Delphi Consensus Panel (DCP) aimed to achieve expert consensus on the percentage reduction in donor skin for autograft that constitutes a clinically meaningful benefit. A two-round DCP of fifteen US burn surgeons was conducted via a web-based survey platform. Fourteen panelists (93.3%) completed both rounds. In Round 2, consensus, defined as ≥70% agreement, was achieved for five of the seven consensus statements. All panelists agreed that a clinically meaningful reduction in the amount of donor skin required would facilitate wound management and decrease donor site morbidity experienced by patients. Furthermore, based on three treatment scenarios, consensus was achieved for a clinically meaningful reduction in the amount of donor skin required for autograft for the adult population in deep partial-thickness and full-thickness burns. Findings from this DCP indicate that an innovative cellular and/or tissue product that would reduce the needed amount of donor skin, by the identified thresholds, has the potential to improve the outcomes for patients with severe burn injuries in a meaningful way.Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

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