• Med. Clin. North Am. · Mar 1986

    Review

    Autoantibodies and their relation to rheumatic diseases.

    • G A McCarty.
    • Med. Clin. North Am. 1986 Mar 1; 70 (2): 237261237-61.

    AbstractThe use of tissue culture substrates for immunofluorescence determinations of nuclear, cytoplasmic, and mitotic cell-related autoantibodies has resulted in the delineation of diverse new specificities, whose clinical correlates are now becoming apparent. This review details both major and minor autoantibody specificities, the status of knowledge regarding their target antigens, and the relation of these serologic systems to distinctive rheumatic disease syndromes.

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