• Yuan Zhang, Shu Wang, Wei Ding, Yao Meng, Huiting Hu, Zhenhua Liu, Xianwei Zeng, Yuguang Guan, and Minzhong Wang.
• Dalian Medical University, Dalian, Liaoning 116044, China; Department of Pediatric Hematology-Oncology, Dalian Municipal Women and Children's Medical Center, Dalian, Liaoning 116037, China.
• J Psychosom Res. 2020 Nov 1; 138: 110253.

ObjectiveIn this study, the authors analyzed the status of anxiety depression and insomnia symptoms and influential factors in the work resumption period of Coronavirus disease 2019 (COVID-19).MethodsA multicenter cross-sectional survey was conducted from March 2, 2020 to March 8, 2020 in Shandong Province, China, using quota sampling combined with snowball sampling. The Generalized Anxiety Disorder-7 (GAD-7), the Patient Health Questionnaire-9 (PHQ-9), and the Insomnia Severity Index (ISI) were used to assess the anxiety, depression, and insomnia symptoms. The multivariate logistic regression analysis was used to explore the influential factors.ResultsA total of 4000 invitations were sent from three centers, 3237 valid questionnaires were received. Based on GAD-7, PHQ-9, and ISI scales, 19.5%-21.7% of the participants had anxiety, depression, or insomnia symptoms; 2.9%-5.6% had severe symptoms. Besides, 2.4%, 4.8%, and 4.5% of the participants had anxiety-depression, anxiety-insomnia, or depression-insomnia combined symptoms. The scores of anxiety and insomnia symptoms, along with scores of depression and insomnia symptoms were positively correlated in these samples. Aged 50-64 years and outside activities once in ≥30 days were risk factors of anxiety, depression, and insomnia symptoms in common. During the epidemic, 17.4% of the participants had received psychological interventions, and only 5.2% had received individual interventions.ConclusionsThe incidence of psychological distress increased during the outbreak of COVID-19 in the work resumption period than the normal period. Current psychological interventions were insufficient; target psychological interventions should be conducted in time.Copyright © 2020 Elsevier Inc. All rights reserved.

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