• Stephan A Munich, Maxim Mokin, Kenneth V Snyder, Adnan H Siddiqui, L Nelson Hopkins, and Elad I Levy.
• *Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York; ‡Department of Neurosurgery, Gates Vascular Institute at Kaleida Health, Buffalo, New York; §Departments of Neurology and Neurosurgery, University of South Florida College of Medicine, Tampa, Florida; ¶Department of Radiology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York; ‖Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York; #Toshiba Stroke and Vascular Research Center, University at Buffalo, State University of New York; **Jacobs Institute, Buffalo, New York.
• Neurosurgery. 2015 Sep 1;77(3):313-20.

AbstractEndovascular treatment for acute ischemic stroke has changed remarkably over the past decade. Beginning with IA thrombolytic administration, endovascular strategies have evolved to include aspiration, self-expanding intracranial stents, and now retrievable stents. With the recent publication of 5 randomized, controlled studies (MR CLEAN, EXTEND-IA, ESCAPE, SWIFT PRIME, and REVASCAT), mechanical thrombectomy, when used in combination with IV tPA, has demonstrated a significant radiographic and clinical benefit over traditional strategies with IV tPA alone. These results have placed endovascular therapy at the forefront of stroke treatment, redefining the standard of care.

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