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- Kaiyu Huang, Shuang Liang, Dong Han, Rubao Guo, Lei Chen, and Antoine Grellet.
- Department of Acupuncture, Ningbo Municipal Hospital of TCM, Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo.
- Medicine (Baltimore). 2020 Jan 1; 99 (3): e18902.
BackgroundRestless legs syndrome (RLS) is a neurological disorder that causes an irresistible urge to move the legs. An increasing number of studies have been published in recent years to support the effectiveness of acupuncture for RLS. We will conduct a comprehensive systematic review and meta-analysis to evaluate the evidence of randomized controlled trials for acupuncture treatment of RLS.MethodsThe following electronic databases will be searched: PubMed, Embase, Web of Science, Cochrane Library, the China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and China Science and Technology Journal Database. The range of publication time will be from the inception of the database to September 2019. Two reviewers will independently conduct article selection, data collection, and risk of bias evaluation. Any disagreement will be resolved by discussion with the third reviewer. Review Manager Software 5.3 will be used for meta-analysis. The Cochrane risk of bias tool will be used to assess the risk of bias.ResultsThis study will provide a high-quality evidence to assess the effectiveness and safety of acupuncture for RLS.ConclusionsThis systematic review will explore whether acupuncture is an effective and safe intervention for RLS.RegistrationPROSPERO CRD42019148948.
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