• Tianzi Li, Aili Lv, Na Xu, Mei Huang, and Yan Su.
• Health Science Center, Xi'an Jiaotong University.
• Medicine (Baltimore). 2020 Dec 11; 99 (50): e23129e23129.

BackgroundExercise training has a lot of potential benefits for hemodialysis patients. And some guidelines emphasize the importance of exercise for maintenance hemodialysis. However, there are many barriers to encourage hemodialysis patients to increase their level of physical activity. A broader understanding of the specific barriers is needed.MethodsMEDLINE, EMBASE, Web of Science, CINAHL, PsycINFO, PubMed, CBM, CNKI, and WangFang will be searched electronically. The Reference lists of included studies will be retrieved manually. If the study is designed with qualitative or mixed methods and directly explores the factors related to the exercise of dialysis patients, the study will be selected. The Critical Appraisal Skills Programme Qualitative Checklist will be applied for the study appraisal. The study search, selection and evaluation of the study will be conducted by 2 independent reviewers. Thematic synthesis will be used for synthesizing the findings of the primary studies.ResultsThis study will provide a high-quality synthesis to examine the barriers and facilitators affecting exercise in hemodialysis patients from the perspective of patients, caregivers, and health care providers.ConclusionThis systematic review will contribute to the in-depth understanding of barriers and facilitators affecting exercise in hemodialysis patients, and improve the prognosis of this population.Ethic And DisseminationThe content of this article does not involve moral approval or ethical review because no individual data will be collected.Prospero RegistrationCRD42020200278. (https://www.crd.york.ac.uk/prospero/#recordDetails).

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