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- Anant Mohan, Rita Sood, Nasir Shariff, Manpreet Singh Gulati, Siddharth Datta Gupta, and Amit Kumar Dutta.
- Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
- Am. J. Med. Sci. 2004 Sep 1; 328 (3): 170-2.
AbstractSarcoidosis is a multisystemic granulomatous disease of unknown origin occurring worldwide and affecting people of all races and ages. This disease manifests most frequently with bilateral hilar lymphadenopathy, pulmonary infiltrates, and skin and ocular lesions. Granulomatous inflammation of the spleen is common in patients with sarcoidosis, but splenic enlargement is unusual and massive splenomegaly quite rare. Splenomegaly is usually homogeneous, but multiple low-attenuating nodular lesions are occasionally seen and easily mistaken for lymphoma, metastases, or infections such as tuberculosis. We describe an unusual case of sarcoidosis in a woman who presented with massive splenomegaly with extensive nodularity that cleared completely with corticosteroid therapy.
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