• Mehmet Kaplan, Ozge Ozcan Abacýoglu, Fethi Yavuz, Gizem Ilgýn Kaplan, Betül Düzen, Nurbanu Bursa, and Ferhat Zorlu.
• Gaziantep University School of Medicine, Department of Cardiology. 27100, Gaziantep, Turkey.
• Rev Assoc Med Bras (1992). 2020 Dec 1; 66 (12): 1707-1711.

ObjectiveThe aim of this study was to investigate the association between intraocular pressure (IOP) and premature atherosclerotic coronary artery disease (PACAD) by comparing central corneal thicknesses (CCTs) measurements.MethodsOne hundred-eighty-six subjects were enrolled in this cross-sectional study, 100 in the PACAD group and 86 in the control group. All participants underwent a physical examination and routine biochemical tests. Ophthalmological examinations, including IOP and CCTs measurements, were performed for each subject. Additionally, pulse wave velocity measurements were obtained and recorded.ResultsParticipants with PACAD showed significantly higher IOP values than those without atherosclerosis (p = 0.001), and there was no statistically significant difference between the groups in terms of CCT (p = 0.343). Also, pulse wave velocity (PWV) values were statistically significantly higher in the PACAD group (p = 0.001). High IOP was not significantly associated with metabolic syndrome parameters (p > 0.05).ConclusionsA relationship was found between PACAD and IOP, but CCTs were not associated with PACAD. The IOP measurement is affected by CCT; therefore, CCT is used to correct IOP values. To our knowledge, this is the first study to report a positive relationship between PACAD and IOP based on CCTs measurements.

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