• Voprosy virusologii · May 2002

    Review

    [Intranasal vaccination with live measles vaccines within the framework of measles eradication strategy].

    • V A Liashchenko and N V Iuminova.
    • Vopr. Virusol. 2002 May 1; 47 (3): 7-10.

    AbstractThe authors discuss the possibility of intranasal revaccination with live measles vaccine. Intranasal vaccination is no less effective than subcutaneous. It induces generalized immune response and formation of anti-measles IgA in the nasopharyngeal mucosa. Immunomodulating side effects of intranasal vaccination are less pronounced than those of subcutaneous one. The intranasal method of vaccination is safer than the inhalation method, which involves exposure of the bronchial mucosa to the live measles virus. The efficiency of mucosal measles vaccine can be increased by adding this or that adjuvant to the vaccine.

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