• Surg. Clin. North Am. · Aug 1985

    Review Clinical Trial

    Therapy of critically ill postoperative patients based on outcome prediction and prospective clinical trials.

    • W C Shoemaker, R D Bland, and P L Appel.
    • Surg. Clin. North Am. 1985 Aug 1; 65 (4): 811-33.

    AbstractAn objective physiologic approach to therapy of high-risk postoperative patients was developed using survival as the criterion to determine the relative importance of variables and optimal goals for these variables. A protocol, based on a branch chain decision tree, also was developed from outcome data. When tested prospectively against the standard of care, this protocol markedly reduced mortality and morbidity.

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