• Infect Control Hosp Epidemiol · Dec 2020

    The utility of chest computed tomography (CT) and RT-PCR screening of asymptomatic patients for SARS-CoV-2 prior to semiurgent or urgent hospital procedures.

    • Aditya S Shah, Lara A Walkoff, Ronald S Kuzo, Matthew R Callstrom, Michael J Brown, Michael L Kendrick, Bradly J Narr, and Elie Berbari.
    • Division of Infectious Disease, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
    • Infect Control Hosp Epidemiol. 2020 Dec 1; 41 (12): 1375-1377.

    ObjectivePresently, evidence guiding clinicians on the optimal approach to safely screen patients for coronavirus disease 2019 (COVID-19) to a nonemergent hospital procedure is scarce. In this report, we describe our experience in screening for SARS-CoV-2 prior to semiurgent and urgent hospital procedures.DesignRetrospective case series.SettingA single tertiary-care medical center.ParticipantsOur study cohort included patients ≥18 years of age who had semiurgent or urgent hospital procedures or surgeries.MethodsOverall, 625 patients were screened for SARS-CoV-2 using a combination of phone questionnaire (7 days prior to the anticipated procedure), RT-PCR and chest computed tomography (CT) between March 1, 2020, and April 30, 2020.ResultsOf the 625 patients, 520 scans (83.2%) were interpreted as normal; 1 (0.16%) had typical features of COVID-19; 18 scans (2.88%) had indeterminate features of COVID-19; and 86 (13.76%) had atypical features of COVID-19. In total, 640 RT-PCRs were performed, with 1 positive result (0.15%) in a patient with a CT scan that yielded an atypical finding. Of the 18 patients with chest CTs categorized as indeterminate, 5 underwent repeat negative RT-PCR nasopharyngeal swab 1 week after their initial swab. Also, 1 patient with a chest CT categorized as typical had a follow-up repeat negative RT-PCR, indicating that the chest CT was likely a false positive. After surgery, none of the patients developed signs or symptoms suspicious of COVID-19 that would indicate the need for a repeated RT-PCR or CT scan.ConclusionIn our experience, chest CT scanning did not prove provide valuable information in detecting asymptomatic cases of SARS-CoV-2 (COVID-19) in our low-prevalence population.

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