• Terapevt Arkh · Jul 2020

    [The balance of proinflammatory cytokines and Treg cells in chronic glomerulonephritis].

    • N V Chebotareva, A A Vinogradov, A A Gindis, I N Bobkova, W Cao, and L V Lysenko.
    • Sechenov First Moscow State Medical University (Sechenov University).
    • Terapevt Arkh. 2020 Jul 9; 92 (6): 46-52.

    AbstractChronic glomerulonephritis (CGN) is a disease with a steadily progressing course, which is based on inflammation with the activation of immune cells. The severity of the inflammatory reaction in the kidney tissue is determined by the balance of locally pro-inflammatory factors and protective mechanisms, which include anti-inflammatory cytokines and T-regulatory lymphocytes (Treg). The study of processes that can modulate the severity of inflammation in the kidney is of particular interest for understanding the basic patterns of CGN progression.

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