• Kidney Int. Suppl. · Nov 1991

    Relationship of anemia to Balkan endemic nephropathy.

    • A Hrabar, S Ceović, B Aleraj, D Cvoriscec, and P W Hall.
    • Croatian Institute of Public Health, Zagreb, Yugoslavia.
    • Kidney Int. Suppl. 1991 Nov 1; 34: S44-5.

    AbstractAnemia has been reported to be an early sign of Balkan endemic nephropathy (BEN) occurring before the serum creatinine is elevated. This study was designed to determine if anemia occurred more frequently in an otherwise 'healthy' population living in an area where BEN is endemic when compared to a control population. Also, we wished to determine if any relationship existed between anemia and beta 2-microglobulinuria (beta 2mu) in these populations. The prevalence of anemia in the control village population was 7%, compared to 21.4% of the at-risk village population. These data suggest that anemia is a part of the pathophysiologic picture of endemic nephropathy, and that anemia can be found in an early, non-azotemic phase of the kidney disease.

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