• J Am Osteopath Assoc · Feb 1996

    Case Reports

    Paraneoplastic intestinal pseudo-obstruction, mononeuritis multiplex, and sensory neuropathy/neuronopathy.

    • D A Simpson, A M Pawlak, L Tegmeyer, C Doig, and D Cox.
    • Michigan Institute for Neurological Disorders, Farmington Hills 48334, USA.
    • J Am Osteopath Assoc. 1996 Feb 1; 96 (2): 125-8.

    AbstractA patient with diffuse intestinal pseudo-obstruction consisting of gastric paresis and impaired small and large bowel motility, mononeuropathy multiplex, and sensory neuropathy/neuronopathy was found to have small-cell carcinoma of the lung. The clinical symptoms were thought to be consistent with paraneoplastic neuropathy, and high antineuronal and anti-calcium channel antibodies led to the diagnosis of small-cell carcinoma of the lung. Identification of paraneoplastic neuropathy is important, because early treatment may halt the progression of the underlying carcinoma.

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