• Indian pediatrics · Apr 2018

    Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis.

    • Mullai Baalaaji, Muralidharan Jayashree, Karthi Nallasamy, Sunit Singhi, and Arun Bansal.
    • Pediatric Emergency and Intensive Care Units, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
    • Indian Pediatr. 2018 Apr 15; 55 (4): 311-314.

    ObjectiveTo identify predictors and outcome of acute kidney injury (AKI) in children with diabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU).MethodsRetrospective case review of 79 children with DKA admitted between 2011-2014.ResultsTwenty eight children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone. Serum chloride at 24 hours was independently associated with AKI. Children with AKI had prolonged acidosis and PICU stay and higher mortality.ConclusionMajority of children with AKI and DKA, recover with hydration. Hyperchloremia at 24 hours had independent association with AKI, although cause-effect relation could not be ascertained.

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