• Catharine Wang, Ananda Sen, Mack T Ruffin, Donald E Nease, Robert Gramling, Louise S Acheson, Suzanne M O'Neill, Wendy S Rubinstein, and Family Healthware™ Impact Trial (FHITr) Group.
• Department of Community Health Sciences, Boston University School of Public Health, Boston, MA 02118, USA. clwang@bu.edu
• Am J Prev Med. 2012 Oct 1; 43 (4): 392-8.

BackgroundFamily Healthware™, a tool developed by the CDC, is a self-administered web-based family history tool that assesses familial risk for six diseases (coronary heart disease; stroke; diabetes; and colon, breast, and ovarian cancers) and provides personalized prevention messages based on risk. The Family Healthware Impact Trial (FHITr) set out to examine the clinical utility of presenting personalized preventive messages tailored to family history risk for improving health behaviors.PurposeThe purpose of this study was to examine the impact of Family Healthware on modifying disease risk perceptions, particularly among those who initially underestimated their risk for certain diseases.DesignA total of 3786 patients were enrolled in a cluster-randomized trial to evaluate the clinical utility of Family Healthware.Setting/ParticipantsParticipants were recruited from 41 primary care practices among 13 states between 2005 and 2007.Main Outcome MeasuresPerceived risk for each disease was assessed at baseline and 6-month follow-up using a single-item comparative risk question. Analyses were completed in March 2012.ResultsCompared to controls, Family Healthware increased risk perceptions among those who underestimated their risk for heart disease (15% vs 9%, p<0.005); stroke (11% vs 8%, p<0.05); diabetes (18% vs 11%, p<0.05); and colon cancer (17% vs 10%, p=0.05) but not breast or ovarian cancers. The majority of underestimators did not shift in their disease risk perceptions.ConclusionsFamily Healthware was effective at increasing disease risk perceptions, particularly for metabolic conditions, among those who underestimated their risk. Results from this study also demonstrate the relatively resistant nature of risk perceptions.Trial RegistrationThis study is registered at clinicaltrials.govNCT00164658.Copyright © 2012 American Journal of Preventive Medicine. All rights reserved.

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