• Medicine · Dec 2020

    Meta Analysis

    Relationship between long non-coding RNA and prognosis of patients with coronary heart disease after percutaneous coronary intervention: A protocol for systematic review and meta-analysis.

    • Fei Wang, Xiaoqing Cai, Piqi Jiao, Yan Liu, Bin Yuan, Peng Zhang, Hongbin Liu, and Ling Ma.
    • Department of Cardiovascular Medicine, 940th Hospital of PLA Joint Service Support Force, Lanzhou, Gansu, China.
    • Medicine (Baltimore). 2020 Dec 18; 99 (51): e23525e23525.

    BackgroundLong non-coding RNA (lncRNA) can predict the prognosis of patients with coronary heart disease (CHD) after obtaining percutaneous coronary intervention (PCI), while this conclusion still needs to be further confirmed. Therefore, this study attempted to explore the relationship between lncRNA and prognosis in CHD patients after PCI.MethodsThe database was retrieved from China National Knowledge Infrastructure (CNKI), Chinese Biomedical literature Database (CBM), Chinese Scientific and Journal Database (VIP), Wan Fang database, PubMed, and EMBASE. Hazard ratios (HRs) and its 95% confidence interval (CIs) were applied to assess the prognostic effects of lncRNA on overall survival (OS). RevMan 5.3 and STATA 16.0 software were used to perform meta-analysis.ResultsThe results of this meta-analysis would be submitted to peer-reviewed journals for publication.ConclusionThis review provided a comprehensive overview of the relationship between lncRNA and prognosis in CHD patients after PCI, and offered recommendations for clinical practices or guidelines.Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.

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