• Yajing Zhang, Xingwei He, Shasha Hu, Songfeng Hu, Fan He, Yu Shen, Fenfen Zhao, Qin Zhang, Tingping Liu, and Changkang Wang.
• College of Acupuncture-Moxibustion and Tuina, Jiangxi University of Traditional Chinese Medicine.
• Medicine (Baltimore). 2020 Dec 18; 99 (51): e23598e23598.

Background: Post-stroke insomnia (PSI) is a serious problem which has significant adverse effects on the subsequent recovery of patients and the quality of their daily life. Massage is effective in improving the quality of sleep for stroke patients displaying no significant adverse reactions. Up to now, however, there are still no systematic studies conducted to provide compelling evidence for its effectiveness in treating PSI. Allowing for this, this project is purposed to make a thorough summary of the efficacy of massage therapy in treating PSI and the safety of this practice.Methods: Without considering the status of publication and language, a meticulous search will be conducted, covering the Web of Science, the Cochrane Library search, PubMed, EMBASE, Chinese biomedical literature database, Chongqing VIP Database for Chinese Technical Periodicals, China National Knowledge Infrastructure, and Wanfang. All randomized controlled trials of PSI will be retrieved. The deadline is set as October 23, 2020. The team will be comprised of 2 experienced researchers who will apply RevMan V.5.3 software to conduct literature selection, data collection, data analysis, and data synthesis, respectively. In addition, the Cochrane risk Assessment tool will be taken as the top choice to evaluate the quality of the trials involved in this study.Results: The effectiveness and safety of massage therapy intended for PSI will be subject to a systematic evaluation under this program.Conclusion: It will be substantiated in this review whether massage therapy is a reliable intervention for PSI by examining the evidence collected.Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.

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