• Christophe Dubois, Tom Adriaenssens, Giovanni Ughi, Stefanus Wiyono, Johan Bennett, Mark Coosemans, Bert Ferdinande, Peter Sinnaeve, Jan D'hooge, and Walter Desmet.
• Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium. christophe.dubois@uzleuven.be
• Catheter Cardiovasc Interv. 2013 Feb 1; 81 (3): E155-64.

ObjectivesWe evaluated healing responses with optical coherence tomography (OCT), and clinical and angiographic outcome after bifurcation stenting with the TRYTON Side-Branch Stent™.BackgroundDedicated bifurcation stents have been proposed as a potential alternative for treatment of true coronary bifurcation lesions.MethodsWe treated 20 consecutive patients with coronary bifurcation lesions and significant involvement of the side-branch (SB) with the TRYTON Stent and an additional XIENCE-V™ everolimus-eluting stent. At 9 months, we assessed the ratio of uncovered to total stent struts (RUTSS) with OCT, angiographic late luminal loss (LLL), and in-stent and in-segment restenosis. Clinical endpoints at 1 year included major adverse cardiac events (MACE) and their components [target lesion revascularization (TLR), myocardial infarction (MI), and cardiac death].ResultsLLL (N = 16) was 0.34 (0.17-0.46), 0.29 (0.24-0.48) and 0.57 (0.29-0.73) mm in the proximal main vessel (MV), distal MV and SB, respectively. In-bifurcation binary in-stent restenosis occurred in four patients (25%), in-segment restenosis in five (31.25%). The RUTSS (N = 13) was 4.0 ± 5.8, 0.7 ± 1.3, 0, and 2.5 ± 3.6% in the proximal MV, distal MV, SB, and polygon of confluence, respectively. At 1 year, MACE occurred in 5 (25%) [4 TLR (20%), 3 MI (15%)].ConclusionThe homogeneous stent strut coverage and the low LLL in the MV reflect proper healing characteristics of the TRYTON Stent in combination with the XIENCE-V™ stent. However, proximal MV edge and ostial SB restenoses together with overall clinical outcomes do not fulfill expectations of a dedicated bifurcation stent. © 2012 Wiley Periodicals, Inc.Copyright © 2012 Wiley Periodicals, Inc.

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