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Expert Rev Anti Infect Ther · Jan 2016
ReviewPrevention of infections in nursing homes: antibiotic prophylaxis versus infection control and antimicrobial stewardship measures.
- Maddalena Giannella, Sara Tedeschi, Michele Bartoletti, and Pierluigi Viale.
- a Clinic of Infectious Diseases, Department of Medical and Surgical Sciences, University of Bologna , Bologna , Italy.
- Expert Rev Anti Infect Ther. 2016 Jan 1; 14 (2): 219-30.
AbstractBecause of the lack of structural and human resources for implementing more effective and safe preventive procedures, antimicrobial prophylaxis is often used to prevent infections in nursing homes. However, if data on the efficacy of antibiotic prophylaxis in nursing homes are null, there is a plenty of evidence that the inappropriate use of antimicrobials in this setting is associated with a high rate of colonization and infection with multi-drug-resistant organisms (MDROs), and of Clostridium difficile infection (CDI). Here, we have reviewed the infection epidemiology, the burden of MDROs and CDI, the antibiotic use and some potential infection preventive measures in nursing homes, pointing up the peculiarities of this setting and the absolute need of a more prudential use of antimicrobials.
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