• J. Cardiothorac. Vasc. Anesth. · Feb 2022

    Review

    Whole-Lung Lavage-a Narrative Review of Anesthetic Management.

    • Santiago M Mata-Suarez, Agustina Castro-Lalín, Santiago Mc Loughlin, Juan De Domini, and Juan C Bianco.
    • Department of Anesthesiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. Electronic address: santiago.mata@hospitalitaliano.org.ar.
    • J. Cardiothorac. Vasc. Anesth. 2022 Feb 1; 36 (2): 587-593.

    AbstractPulmonary alveolar proteinosis is a rare disease characterized by progressive accumulation of lipoprotein material in the alveoli as a result of a dysfunction in surfactant clearance. The whole-lung lavage procedure is considered the current standard of care and consists of the sequential lavage of both lungs for mechanical removal of residual material in the alveoli. However, a lack of standardization has resulted in different procedural techniques among institutions. Even though whole-lung lavage is considered to be a safe procedure, unforeseen complications might occur, and proper knowledge of physiologic implications may allow clinicians to establish the appropriate therapy. This review provides an insight into the underlying physiology of the disease, the technical details of the procedure from an anesthesiologist's perspective, and discussion of potential intraoperative complications.Copyright © 2020 Elsevier Inc. All rights reserved.

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