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Neuromuscul. Disord. · Nov 2006
Case ReportsOutpatient continuous inotrope infusion as an adjunct to heart failure therapy in Duchenne muscular dystrophy.
- Linda H Cripe, Brent J Barber, Robert L Spicer, Brenda L Wong, Norbert Weidner, D Woodrow Benson, and Larry W Markham.
- Division of Cardiology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA. L.Cripe@CCHMC.org
- Neuromuscul. Disord. 2006 Nov 1; 16 (11): 745-8.
AbstractWe report the use of continuous intravenous inotrope infusion as a palliative management strategy for the treatment of symptomatic, refractory, end stage cardiac dysfunction in patients with Duchenne muscular dystrophy. Milrinone and/or dobutamine administered by continuous intravenous infusion provided symptomatic and objective cardiovascular improvement up to 30 months in 3 individuals with Duchenne muscular dystrophy and severe dilated cardiomyopathy. Continuous inotrope infusion should be considered a practical treatment strategy for end stage cardiac dysfunction in Duchenne muscular dystrophy patients when cardiac transplantation is not a viable option.
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