• Internal medicine · Jun 2021

    Case Reports

    Heerfordt's Syndrome Associated with Trigeminal Nerve Palsy and Reversed Halo Sign.

    • Go Makimoto, Keita Kawakado, Masamoto Nakanishi, Tomoki Tamura, Minori Noda, Satoko Makimoto, Yumiko Sato, and Shoichi Kuyama.
    • Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan.
    • Intern. Med. 2021 Jun 1; 60 (11): 1747-1752.

    AbstractHeerfordt's syndrome is a rare subtype of sarcoidosis and features a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. Cases with two of three symptoms are called "incomplete Heerfordt's syndrome." Heerfordt's syndrome involving other cranial nerve symptoms is relatively rare. We herein report a case of incomplete Heerfordt's syndrome presenting with trigeminal nerve palsy and a reversed halo sign, a rare manifestation of pulmonary sarcoidosis. The histological diagnosis following a biopsy of the parotid gland and endobronchial ultrasound-guided trans-bronchial needle aspiration of the mediastinal lymph nodes was sarcoidosis. The symptoms and lung lesions improved after corticosteroid therapy.

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