• Christopher T Leffler, Kamyar Vaziri, Stephen G Schwartz, Kara M Cavuoto, Craig A McKeown, Krishna S Kishor, and Adam C Janot.
• Department of Ophthalmology, Virginia Commonwealth University Medical Center, Richmond, Virginia. Electronic address: chrislefflermd@gmail.com.
• Am. J. Ophthalmol. 2016 Feb 1; 162: 159-166.e9.

PurposeTo determine predictors of reoperation and abnormal binocularity outcomes (including amblyopia and diplopia) following pediatric strabismus surgery.DesignRetrospective cross-sectional study.Methodssetting: Review of a national insurance database.Study PopulationChildren under age 18 years having strabismus procedures between 2007 and 2013.InterventionsAdjustable- or fixed-suture strabismus surgery, or botulinum toxin injection.Outcome MeasuresReoperation or diagnosis of abnormal binocularity in the first postoperative year.ResultsOf 11 115 children having strabismus procedures, 851 (7.7%) underwent reoperation. The reoperation rate was 7.4% for fixed-suture surgeries, 9.6% for adjustable-suture surgeries (P = .18), and 44.9% for botulinum injections (P < .001). Age under 2 years was associated with higher reoperation and abnormal binocularity rates (P < .001). For horizontal strabismus, the postoperative abnormal binocularity rate was 12.8% for fixed-suture surgery and 26.5% for botulinum injection (P = .005). Reoperation rates tended to be higher with adjustable sutures (odds ratio [OR] 1.69, 95% confidence interval [CI] 0.94-3.03, P = .08) or botulinum toxin injection (OR 10.36, 95% CI 5.75-18.66, P < .001) and lower with 3- or 4-muscle surgery (P = .001). Esotropia, hyperopia, and botulinum injection were independently associated with higher rates of postoperative abnormal binocularity (P ≤ .005). For vertical surgeries, predictors of reoperation were adjustable-suture use (OR 2.51, P = .10) and superior oblique surgery (OR 2.36, P < .001).ConclusionsAdjustable sutures were not associated with a lower reoperation rate in children. Younger age, esotropia, hyperopia, and botulinum injection were associated with postoperative abnormal binocularity. Superior oblique surgery and botulinum injection were associated with higher rates of reoperation.Copyright © 2016 Elsevier Inc. All rights reserved.

36 keywords...

hide…