• Arch Phys Med Rehabil · Oct 2018

    Personality, High-Risk Behaviors, and Elevated Risk of Unintentional Deaths Related to Drug Poisoning Among Individuals With Spinal Cord Injury.

    • James S Krause, Yue Cao, Nicole D DiPiro, and Emma Cuddy.
    • College of Health Professions, Medical University of South Carolina, Charleston, SC. Electronic address: krause@musc.edu.
    • Arch Phys Med Rehabil. 2018 Oct 1; 99 (10): 1941-1948.

    ObjectiveTo identify risk and protective factors for unintentional death related to drug poisoning from prescription medications, including opioid-related deaths, and death due to all other causes among participants with spinal cord injury (SCI).DesignProspective cohort study.SettingLarge specialty hospital in the southeastern United States.ParticipantsTwo cohorts of SCI participants (N=3070) (>18y) with chronic (>1y) traumatic SCI. Cohort 1 was enrolled in 1997-1998 (n=1386), and cohort 2 was enrolled in 2007-2009 (n=1684).InterventionsN/A.Main Outcome MeasuresParticipants completed self-report assessments including multiple behavioral variables (alcohol, smoking, prescription medication), as well as the Zuckerman-Kuhlman Personality Questionnaire (ZKPQ). The primary outcome is unintentional death related to drug poisoning. Mortality status was determined as of December 31, 2014, using the National Death Index. The Centers for Disease Control guidelines were used for classifying participants into 3 groups: (1) unintentional death related to drug poisoning, (2) other death, and (3) alive.ResultsThere were 690 deaths (23%), including 24 unintentional deaths related to drug poisoning (11 from opioids). Binge drinking, medication usage total score, and impulsive-sensation seeking were risk factors for unintentional death related to drug poisoning, whereas the ZKPQ activity scale was protective. Risk factors for other causes of death included older age, greater injury severity, being nonambulatory, regular smoker, medication use total score, and greater neuroticism-anxiety scale scores.ConclusionsUnintentional deaths related to prescription drug overdose are associated with a set of risk factors that differs in meaningful ways from risk of death due to other causes after SCI, and these differences hold the key to prevention strategies.Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…