• Revista médica de Chile · Jul 2020

    Review

    [Osteonecrosis of the jaws].

    • Camila Foncea, Kristine von Bischhoffshausen, Cristián Teuber, Hernán Ramírez, Ignacio Goñi, Cesar Sánchez, Ignacio N Retamal, and Alex Vargas.
    • Departamento de Cirugía Oncológica y Maxilofacial, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
    • Rev Med Chil. 2020 Jul 1; 148 (7): 983-991.

    AbstractMedication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.

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