• Curr Med Res Opin · Jan 2016

    Letter Case Reports

    Clinical use of plasma chitotriosidase in severe sepsis.

    • Carlo Chiarla, Ivo Giovannini, Daniela Antuzzi, Andrea Piras, Francesco Ardito, and Felice Giuliante.
    • a a CNR-IASI Center for the Pathophysiology of Shock, Catholic University of the Sacred Heart, Agostino Gemelli Hospital , Rome , Italy.
    • Curr Med Res Opin. 2016 Jan 1; 32 (2): 273-6.

    AbstractPlasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.

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