• Acta Anaesthesiol Scand · May 2021

    Effects of inhaled nitric oxide in COVID-19-induced ARDS - Is it worthwhile?

    • Christopher Lotz, Ralf M Muellenbach, Patrick Meybohm, Haitham Mutlak, Philipp M Lepper, Caroline-Barbara Rolfes, Asghar Peivandi, Jan Stumpner, Markus Kredel, Peter Kranke, Iuliu Torje, and Christian Reyher.
    • Department of Anaesthesiology and Critical Care Medicine, University of Würzburg, Würzburg, Germany.
    • Acta Anaesthesiol Scand. 2021 May 1; 65 (5): 629-632.

    BackgroundChanges in pulmonary hemodynamics and ventilation/perfusion were proposed as hallmarks of Coronavirus disease 2019 (COVID-19)-induced acute respiratory distress syndrome (ARDS). Inhaled nitric oxide (iNO) may overcome these issues and improve arterial oxygenation.MethodsWe retrospectively analyzed arterial oxygenation and pulmonary vasoreactivity in seven COVID-19 ARDS patients receiving 20 ppm iNO for 15-30 minutes.ResultsThe inhalation of NO significantly improved oxygenation. All patients with severe ARDS had higher partial pressures of oxygen and reduced pulmonary vascular resistance. Significant changes in pulmonary shunting were not observed.ConclusionOverall, iNO could provide immediate help and delay respiratory deterioration in COVID-19-induced moderate to severe ARDS.© 2020 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.