• Ir J Med Sci · Mar 2011

    Review Case Reports

    Male lupus: a diagnosis often delayed--a case series and review of the literature.

    • N L Ambrose, G Kearns, and A Mohammad.
    • Rheumatology Department, Beaumont Hospital, Dublin, Ireland. nambrose2001@yahoo.co.uk
    • Ir J Med Sci. 2011 Mar 1; 180 (1): 279-82.

    IntroductionSystemic lupus erythematosus (SLE) is an auto-immune disease that is characterised by autoantibody production. Male lupus is rare, apart from at either end of the age spectrum.AimIn this series, we review the histories of six male lupus patients attending our service.ResultsOur patients presented in middle age and tended to develop haematological abnormalities, renal involvement and neurological manifestations which preceded the onset of their skin and joint complaints. Our patients accrued damage rapidly and overall did badly. They tended to respond sub-optimally to standard treatments. These cases highlight the need an increased awareness that male SLE patients present with a wide variety of symptoms, and that they accrue damage quickly. There is a need for timely diagnosis and appropriate initiation of treatment. This may help avoid preventable organ damage and increase the survival of men with SLE.

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