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The lancet oncology · Mar 2004
Review Historical ArticleOestrogen receptor beta: what it means for patients with breast cancer.
- Valerie Speirs, Pauline J Carder, Sally Lane, David Dodwell, Mark R J Lansdown, and Andrew M Hanby.
- Molecular Medicine Unit, University of Leeds, Leeds, UK. v.speors@leeds.ac.uk
- Lancet Oncol. 2004 Mar 1; 5 (3): 174-81.
AbstractOestrogen receptor (ER) alpha is a well established prognostic marker in breast cancer, and all patients who are ER alpha positive receive tamoxifen as adjuvant endocrine therapy. Although ER alpha predicts a favourable disease outcome, the usefulness of ER beta as a clinical prognostic marker remains to be defined. Here, we outline the history of both ERs and discuss the implications ER beta has to patients with breast cancer.
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