• J Laryngol Otol · Apr 2015

    Spontaneous cerebrospinal fluid leaks in the anterior skull base: a surgical challenge.

    • G Martínez-Capoccioni, R Serramito-García, B Huertas-Pardo, A García-Allut, and C Martín-Martín.
    • Service of ENT-Head and Neck Surgery,Servizo Galego de Saúde,University Hospital Complex of Santiago de Compostela,Santiago de Compostela,Spain.
    • J Laryngol Otol. 2015 Apr 1; 129 (4): 358-64.

    ObjectiveThis retrospective study aimed to evaluate the effective closure rate for spontaneous cerebrospinal fluid leaks with functional endoscopic sinus surgery and identify patient characteristics that may be associated with a need for additional therapy.MethodA retrospective analysis of patients with spontaneous cerebrospinal fluid leaks was performed. Data on the nature of presentation, patient body mass index, defect location and size, intracranial pressure, clinical follow up, and complications were collected.ResultsTwenty-five patients had spontaneous cerebrospinal fluid leaks with evidence of idiopathic intracranial hypertension. The most common sites were the cribriform plate, followed by the ethmoid roof and sphenoid lateral pterygoid recess. All patients underwent endonasal endoscopic surgery to repair the defect. Post-operatively, all patients underwent lumbar drainage and acetazolamide therapy.ConclusionSpontaneous cerebrospinal fluid leaks represent a surgical challenge because of their high recurrence rates. The most important factor for obtaining a successful repair in these patients is reducing their intracranial pressure through nutritional, medical or surgical means.

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