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- Anna F Y Li, Chia-Lin Wang, Hsiao-Yun Tai, Yun-Ju Fu, Fu-Ting Tsai, Yi-Ching Tsai, Yu-Ling Ko, Mei-Jane Li, Chiou-Chyn Lin, and Tai-Jay Chang.
- Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
- J Chin Med Assoc. 2021 Mar 1; 84 (3): 245247245-247.
AbstractThe rapid spread of coronavirus disease (COVID-19) in many countries has caused inconvenience in conducting daily life activities, and even deaths. Dexamethasone is a corticosteroid applied in clinical medicine since 1957, especially in immune therapy fields. Herein, we present the characteristics of Dexamethasone, from molecular mechanisms such as genomic and nongenomic pathways by cellular signal regulations, to clinical applications in various phases of the disease. During COVID-19 pandemic, Dexamethasone given to patients who required oxygen or ventilation therapy showed improved life efficacy.Copyright © 2020, the Chinese Medical Association.
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