• J. Neurol. Neurosurg. Psychiatr. · Feb 2014

    Review

    Depression in glioma: a primer for clinicians and researchers.

    • Alasdair G Rooney, Paul D Brown, Jacob C Reijneveld, and Robin Grant.
    • Edinburgh Centre for Neuro-Oncology, Western General Hospital, , Edinburgh, Scotland, UK.
    • J. Neurol. Neurosurg. Psychiatr.. 2014 Feb 1;85(2):230-5.

    AbstractDepression is one of the leading causes of global disability, and a considerable hidden morbidity among patients with glioma. In this narrative review, we summarise what is currently known about depression in glioma, the main unanswered questions and the types of studies that should be prioritised in order to find out. We conclude by calling for a prospective Phase II study of antidepressants in depressed glioma patients, to test methodologies for a multicentre randomised controlled trial.

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