• Mika Venojärvi, Niko Wasenius, Sirpa Manderoos, Olli J Heinonen, Miika Hernelahti, Harri Lindholm, Jukka Surakka, Jaana Lindström, Sirkka Aunola, Mustafa Atalay, and Johan G Eriksson.
• Turku University of Applied Sciences, Turku, Finland. mika.venojarvi@uef.fi
• Ann. Med. 2013 Mar 1; 45 (2): 162-70.

BackgroundDysfunction of adipose tissue is one of the major factors leading to insulin resistance. Altered adipokine concentration is an early sign of adipose tissue dysfunction. The aim of this study was to assess the impact of exercise intervention on adipokine profile, glycemic control, and risk factors of the metabolic syndrome (MeS) in men with impaired glucose regulation (IGR).MethodsOverweight and obese men with IGR (n =144) aged 40-65 years were studied at baseline and at 12 weeks in a randomized controlled multicenter intervention study. BMI varied from 25.1 to 34.9. The subjects were randomized into one of three groups: 1) a control group (C; n =47), 2) a Nordic walking group (NW; n =48), or 3) a resistance training group (RT; n =49).ResultsLeptin concentrations decreased in the NW group compared to both other groups. Both types of exercise intervention significantly decreased serum chemerin concentrations compared to the C group. In the NW group also body fat percentage, fatty liver index (FLI), and total and LDL cholesterol concentrations decreased compared to the RT group.ConclusionsNordic walking intervention seems to decrease chemerin and leptin levels, and subjects in this intervention group achieved the most beneficial effects on components of MeS.

26 keywords...

hide…