• Stud Health Technol Inform · Jan 2010

    The IT-infrastructure of a biobank for an academic medical center.

    • Andrea Dangl, Sara Y Demiroglu, Jochen Gaedcke, Krister Helbing, Peter Jo, Fabian Rakebrandt, Otto Rienhoff, and Ulrich Sax.
    • University Medical Center, Goettingen, Germany.
    • Stud Health Technol Inform. 2010 Jan 1; 160 (Pt 2): 1334-8.

    AbstractFor high quality research in biomedicine an operable biobank is essential. In order to make optimal use of the material and the huge amount of data a sustainable IT-infrastructure is indispensable. Therefore, we developed a concept for the IT-infrastructure of a biobank for an academic medical center. The conclusions for this concept are deduced from our experience with the biobank and IT-infrastructure of a clinical research unit. Our results indicate that the IT-infrastructure plays a pivotal role in successfully establishing a biobank. Several aspects of the IT-infrastructure are similarly found in other areas as, e.g. data protection and storage and quality management. Finally, we conclude that although a research database is not required for operating a biobank, the need for it will definitely emerge, especially with regard to personalized medicine and high-throughput gene expression analysis.

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