• Semin Pediatr Neurol · Sep 2010

    Review

    Status epilepticus treatment and outcome in children: what might the future hold?

    • Lucyna Zawadzki and Carl E Stafstrom.
    • Department of Neurology, Section of Pediatric Neurology, University of Wisconsin, Madison, WI 53705, USA.
    • Semin Pediatr Neurol. 2010 Sep 1; 17 (3): 201-5.

    AbstractStatus epilepticus is a life-threatening emergency that requires urgent treatment. Over the past decade, numerous advances have been made in the management of status epilepticus. Clinical studies have now established the benefit of early, aggressive treatment of status epilepticus with benzodiazepines in both prehospital and hospital settings. Neuroscientific advances are revealing mechanisms of status epilepticus that could translate into targets for treating acute status epilepticus and even reducing epileptogenesis. This article discusses future trends in the diagnosis, neurobiology, and treatment of status epilepticus.Copyright 2010 Elsevier Inc. All rights reserved.

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