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Korean J Anesthesiol · Oct 2019
Case ReportsAnaphylactic shock after sugammadex administration, induced by formation of a sugammadex-rocuronium complex -a case report.
- Gunn Hee Kim, Won Seop Choi, Ji Eun Kim, Mi Jung Yun, Min Seok Koo, Miyoung Kwon, and Hyungseok Seo.
- Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
- Korean J Anesthesiol. 2019 Oct 1; 72 (5): 495-499.
BackgroundSugammadex is a reversal agent for non-depolarizing neuromuscular blockers and widely used worldwide on account of its rapid and effective reversal from neuromuscular blockade, despite its advantages, multiple cases of sugammadex-induced anaphylactic shock have been reported.CaseA 42-year-old man developed anaphylactic shock in the postanesthesia care unit. Initially, sugammadex was suspected as the causative agent, but an intradermal skin test revealed negative results. A further skin test was performed with sugammadex-rocuronium complex that yielded positive results.ConclusionsAnesthesiologists and healthcare providers should be aware of the possibility of anaphylaxis from the sugammadex-rocuronium complex, as well as from sugammadex or rocuronium alone.
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