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J. Cardiovasc. Pharmacol. · Aug 2020
ReviewCurrent Perspectives of Anticoagulation in Patients With COVID-19.
- Elizabeth M Gavioli, Gabriela Sikorska, Ammy Man, Jay Rana, and Etty Vider.
- Division of Pharmacy, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Brooklyn, NY.
- J. Cardiovasc. Pharmacol. 2020 Aug 1; 76 (2): 146-150.
AbstractThromboembolism and myocardial injury is common in patients with COVID-19. Low-molecular-weight heparin appears to be associated with a good prognosis in patients with COVID-19 and has the ability to reduce coagulation and inflammation markers. Hospitalized patients with COVID-19 should be placed on thromboprophylaxis with the option of full therapeutic anticoagulation or tissue plasminogen activator in high-risk or mechanically ventilated patients. Thromboprophylaxis should also be considered at hospital discharge for high-risk patients. Clinical judgment should be used to evaluate the bleeding and safety risk of anticoagulation in patients with COVID-19 without confirmed data.
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