• Biomed. Pharmacother. · Sep 2020

    Review

    Monoclonal antibody as a potential anti-COVID-19.

    • Leila Jahanshahlu and Nima Rezaei.
    • School of Medical, Zanjan University of Medical Sciences, Zanjan, Iran; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Zanjan, Iran.
    • Biomed. Pharmacother. 2020 Sep 1; 129: 110337.

    AbstractCoronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural similarity of the virus to severe acute respiratory syndrome coronavirus (SARS-CoV) created the potential for understanding disease pathogenesis. Researchers have published reports of specific monoclonal antibodies against to COVID-19 (B38, H4, 47D11) and hope that this method is effective. As well as studies on patients who are plasma therapy, the patient's condition shows improvement. The evidence for these studies is very promising and demonstrates the potential of monoclonal antibody therapy as a therapeutic approach and prevention of covid-19 infection.Copyright © 2020 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

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